The Precision Neuroscience & Neuromodulation (PNN) program at Massachusetts General Hospital (MGH) in Boston focuses on the identification of novel biomarkers and therapeutic approaches for patients with neurological and psychiatric conditions. We work towards developing cognitive enhancement solutions to optimize brain function and behavior, and promote brain health across the lifespan.
The program leverages the combination of multimodal neuroimaging techniques (e.g., fMRI, DTI, ASL, PET), electrophysiology (EEG, EMG), cognitive neuroscience, computational modeling, and noninvasive brain stimulation methods for the investigation of brain circuitry and its relationship to cognitive abilities. The program is centered around the concepts of brain connectomics, network neuroscience and brain plasticity, offering a transversal view of healthy and pathological brain functioning from micro- to meso- and macro-scale. The program also hosts clinical trials in neurological and psychiatric conditions, offering a full spectrum of applications from biomarker discovery to computational simulation and clinical testing.
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